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1H-Indene-1,5-dicarboxylicacid, 1-amino-2,3-dihydro- (168560-79-0)

Identification
Name:1H-Indene-1,5-dicarboxylicacid, 1-amino-2,3-dihydro-
Synonyms:1-Aminoindan-1,5-dicarboxylicacid;AIDA;UPF 523;
CAS:168560-79-0
Molecular Formula: C11H11NO4
Molecular Weight: 221.20934
InChI: InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Molecular Structure: (C11H11NO4) 1-Aminoindan-1,5-dicarboxylicacid;AIDA;UPF 523;
Properties
Density:1.481 g/cm3
Water Solubility:Soluble in 3N HCl or 10% Pyridine; poorly soluble in water,insoluble in alcohol
Solubility:Soluble in 3N HCl or 10% Pyridine; poorly soluble in water,insoluble in alcohol
Appearance:White solid
Biological Activity: A relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu 1a ), having no effect on group II (mGlu 2 ) or group III (mGlu 4 ) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutamate receptors. Centrally active following systemic administration in vivo .
Storage Temperature: 0-6°C
Color: white
Safety Data
Hazard Symbols Xi: Irritant
 

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