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Piperazine,1-[2-(3,4-dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)-,hydrochloride (1:2) (170856-41-4)

Identification
Name:Piperazine,1-[2-(3,4-dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)-,hydrochloride (1:2)
Synonyms:Piperazine,1-[2-(3,4-dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)-,dihydrochloride (9CI); PNU 96415E
CAS:170856-41-4
Molecular Formula: C21H25 F N2 O . 2 Cl H
Molecular Weight: 0
Molecular Structure: (C21H25FN2O.2ClH) Piperazine,1-[2-(3,4-dihydro-1H-2-benzopyran-1-yl)ethyl]-4-(4-fluorophenyl)-,dihydrochloride (9CI); ...
Properties
Biological Activity: Antipsychotic agent. Displays high affinity for dopamine D 4 and serotonergic 5-HT 2A receptors and relatively weak affinity at D 2 receptors (K i values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D 4 , 5-HT 2A , 5-HT 1A , α 1 , D 2 , D 3 , D 1 , α 2 ? and muscarinic receptors respectively). Inhibits exploratory locomotor activity and antagonizes d-amphetamine-induced locomotor stimulation in rats.
Safety Data
 

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