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CP 376395 (175140-00-8)
Identification
Name:
CP 376395
Synonyms:
CP 376395
CAS:
175140-00-8
Molecular Formula:
C21H30N2O.ClH
Molecular Weight:
362.942
Molecular Structure:
Properties
Biological Activity:
Potent and selective CRF 1 receptor antagonist (K i values are 12 and >10000 nM for CRF 1 and CRF 2 receptors respectively). Attenuates CRF-induced activation of the HPA axis in vivo following i.v. administration. Orally active.
Safety Data
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