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L-Prolinamide,N2-[(1-hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-, hydrochloride (1:1) (178925-65-0)

Identification
Name:L-Prolinamide,N2-[(1-hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-, hydrochloride (1:1)
Synonyms:L-Prolinamide,N2-[(1-hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-, monohydrochloride (9CI);APC 366; N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide hydrochloride
CAS:178925-65-0
Molecular Formula: C22H28 N6 O4 . Cl H
Molecular Weight: 0
InChI: InChI=1/C22H28N6O4.ClH/c23-19(30)17-8-4-12-28(17)21(32)16(7-3-11-26-22(24)25)27-20(31)15-10-9-13-5-1-2-6-14(13)18(15)29;/h1-2,5-6,9-10,16-17,29H,3-4,7-8,11-12H2,(H2,23,30)(H,27,31)(H4,24,25,26);1H/t16-,17-;/m0./s1
Molecular Structure: (C22H28N6O4.ClH) L-Prolinamide,N2-[(1-hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-, monohydrochloride (9CI);APC 366; N...
Properties
Flash Point: 458.9°C
Boiling Point: 835.1°Cat760mmHg
Density:g/cm3
Biological Activity: Selective inhibitor of mast cell tryptase (K i = 7.1 μ M) that inhibits tryptase-induced histamine release from human tonsil and lung cells. Reduces airway inflammation and blocks postchallenge airway hyperresponsiveness in vivo .
Flash Point: 458.9°C
Safety Data
 

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