| Identification |
| Name: | 8-Quinolinamine,6-[[2-(1-methylethyl)phenyl]sulfonyl]-5-nitro- |
| Synonyms: | PD 160170 |
| CAS: | 181468-88-2 |
| Molecular Formula: | C18H17 N3 O4 S |
| Molecular Weight: | 371.41028 |
| InChI: | InChI=1/C18H17N3O4S/c1-11(2)12-6-3-4-8-15(12)26(24,25)16-10-14(19)17-13(7-5-9-20-17)18(16)21(22)23/h3-11H,19H2,1-2H3 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 344.8°C |
| Boiling Point: | 646.6°Cat760mmHg |
| Density: | 1.379g/cm3 |
| Refractive index: | 1.658 |
| Biological Activity: | Potent, selective non-peptidic neuropeptide Y 1 receptor antagonist (K i = 48 nM); selective over Y 2 and Y 5 receptors (K i > 10 μ M). Antagonizes NPY-mediated inhibition of cAMP accumulation in SK-N-MC cells (IC 50 = 8.2 nM). |
| Flash Point: | 344.8°C |
| Safety Data |
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