| Identification | |
| Name: | 1H-Indole-1-carboxamide,N-[3-fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)- |
| Synonyms: | SB 228357 |
| CAS: | 181629-93-6 |
| Molecular Formula: | C22H17 F4 N3 O2 |
| Molecular Weight: | 431.38 |
| InChI: | InChI=1/C22H17F4N3O2/c1-31-20-9-13-4-6-29(19(13)11-18(20)22(24,25)26)21(30)28-17-8-15(7-16(23)10-17)14-3-2-5-27-12-14/h2-3,5,7-12H,4,6H2,1H3,(H,28,30) |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 332°C |
| Boiling Point: | 625.4°Cat760mmHg |
| Density: | 1.398g/cm3 |
| Refractive index: | 1.599 |
| Biological Activity: | 5-HT 2C/2B receptor antagonist (pK i values are 7.0, 8.1 and 9.1 at 5-HT 2A , 2B and 2C receptors respectively). Displays inverse agonism in a 5-HT-stimulated PI hydrolysis model of 5-HT 2C receptor function. Orally active in vivo . |
| Flash Point: | 332°C |
| Storage Temperature: | 2-8°C |
| Color: | white |
| Safety Data | |
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