Identification |
Name: | 1-[3-(9H-CARBAZOL-9-YL)PROPYL]-4-(2-METHOXYPHENYL)-4-PIPERIDINOL HYDROCHLORIDE |
Synonyms: | 1-[3-(9H-CARBAZOL-9-YL)PROPYL]-4-(2-METHOXYPHENYL)-4-PIPERIDINOL HYDROCHLORIDE;NNC 05-2090 HYDROCHLORIDE |
CAS: | 184845-43-0 |
Molecular Formula: | C27H31ClN2O2 |
Molecular Weight: | 0 |
InChI: | InChI=1/C27H30N2O2.ClH/c1-31-26-14-7-4-11-23(26)27(30)15-19-28(20-16-27)17-8-18-29-24-12-5-2-9-21(24)22-10-3-6-13-25(22)29;/h2-7,9-14,30H,8,15-20H2,1H3;1H |
Molecular Structure: |
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Properties |
Flash Point: | 342.7°C |
Boiling Point: | 643.1°C at 760 mmHg |
Biological Activity: | GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (K i values are 1.4, 15, 19 and 41 μ M for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at α 1 - and D 2 -receptors (IC 50 values are 266 and 1632 nM respectively). |
Flash Point: | 342.7°C |
Safety Data |
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