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PNU 109291 (187665-60-7)

Identification
Name:PNU 109291
Synonyms:PNU 109291;(S)-3,4-DIHYDRO-1-[2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE
CAS:187665-60-7
Molecular Formula: C24H31N3O3
Molecular Weight: 0
Molecular Structure: (C24H31N3O3) PNU 109291;(S)-3,4-DIHYDRO-1-[2-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-METHYL-1H-2-BENZOPYRAN-6...
Properties
Biological Activity: Potent and selective 5-HT 1D receptor agonist that displays > 600-fold selectivity over 5-HT 1A and 5-HT 2A receptors and no activity at 5-HT 1B , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 6 and 5-HT 7 receptors. Reduces dural plasma extravasation evoked by trigeminal ganglion stimulation.
Safety Data