Identification |
Name: | 5H-Imidazo[4,5-c]pyridine-5-acetamide,2-butyl-3,4-dihydro-N,N-dimethyl-4-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-,potassium salt (1:1) |
Synonyms: | 5H-Imidazo[4,5-c]pyridine-5-acetamide,2-butyl-3,4-dihydro-N,N-dimethyl-4-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-,potassium salt (9CI); EMD 66684 |
CAS: | 187683-79-0 |
Molecular Formula: | C28H30 N8 O2 . K |
Molecular Weight: | 547.05114 |
InChI: | InChI=1/C28H30N8O2.ClH/c1-4-5-10-24-29-23-15-16-35(18-25(37)34(2)3)28(38)26(23)36(24)17-19-11-13-20(14-12-19)21-8-6-7-9-22(21)27-30-32-33-31-27;/h6-9,11-16H,4-5,10,17-18H2,1-3H3,(H,30,31,32,33);1H |
Molecular Structure: |
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Properties |
Flash Point: | 441.9°C |
Boiling Point: | 807.1°Cat760mmHg |
Density: | g/cm3 |
Biological Activity: | Highly potent and very selective non-peptide angiotensin AT 1 receptor antagonist (IC 50 values are 0.7 and > 10000 nM for AT 1 and AT 2 receptors respectively). Potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC 50 = 0.2 nM) and reduces blood pressure in hypertensive rats. |
Flash Point: | 441.9°C |
Safety Data |
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