N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE (189060-98-8)

Identification
Name:	N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
Synonyms:	N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE;NGB 2904 HYDROCHLORIDE;9H-Fluorene-2-carboxamide, N-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyl)-;N-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butyl)-3-fluorenylcarboxamide;Ngb 2904;Ngb-2904
CAS:	189060-98-8
Molecular Formula:	C28H30Cl3N3O
Molecular Weight:	0
InChI:	InChI=1/C28H29Cl2N3O.ClH/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24;/h1-2,5-11,19H,3-4,12-18H2,(H,31,34);1H
Molecular Structure:
Properties
Flash Point:	382.4°C
Boiling Point:	708.8°C at 760 mmHg
Biological Activity:	Potent and selective dopamine D 3 receptor antagonist (K i values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D 3 , D 2 , 5-HT 2 , α 1 , D 4 , D 1 and D 5 receptors respectively). Potently antagonizes quinpirole-stimulated mitogenesis (IC 50 = 6.8 nM). Attenuates cocaine's rewarding effects and inhibits relapse to drug-seeking behavior.
Flash Point:	382.4°C
Safety Data