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4-Piperidinol,1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]- (193359-26-1)

Identification
Name:4-Piperidinol,1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-
Synonyms:1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol;Co 101244; PD 174494; Ro 63-1908
CAS:193359-26-1
Molecular Formula: C21H27 N O3
Molecular Weight: 377.90492
InChI: InChI=1/C21H27NO3.ClH/c1-17-2-4-18(5-3-17)16-21(24)10-12-22(13-11-21)14-15-25-20-8-6-19(23)7-9-20;/h2-9,23-24H,10-16H2,1H3;1H
Molecular Structure: (C21H27NO3) 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol;Co 101244; PD 174494; Ro 63-1...
Properties
Flash Point: 273.1°C
Boiling Point: 527.9°Cat760mmHg
Density:g/cm3
Biological Activity: Novel, potent and selective antagonist of NR2B-containing NMDA receptors (IC 50 values are 0.043, > 100 and > 100 μ M for NR1A/2B, NR1A/2A and NR1A/2C subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro .
Flash Point: 273.1°C
Safety Data