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4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE (193542-65-3)

Identification
Name:4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE
Synonyms:4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE;BX 513 HYDROCHLORIDE
CAS:193542-65-3
Molecular Formula: C28H30Cl2N2O
Molecular Weight: 0
Molecular Structure: (C28H30Cl2N2O) 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE;BX 513 HYDROCHLOR...
Properties
Biological Activity: Selective CCR1 receptor antagonist (K i values are 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors respectively). Inhibits MIP-1 α -induced intracellular calcium mobilization (IC 50 = 2.5 μ M). Also a full inverse agonist at US28, a? HCMV-encoded chemokine receptor.
Safety Data