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Urea,N-(5-chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)- (196868-63-0)

Identification
Name:Urea,N-(5-chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)-
CAS:196868-63-0
Molecular Formula: C18H16 Cl N3 O2
Molecular Weight: 0
Molecular Structure: (C18H16ClN3O2) IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea;PQ401
Properties
Transport:UN 2811 6.1/PG 3
Biological Activity: Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC 50 value of 12 μ M. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo .
Storage Temperature: 2-8°C
Safety Data
Hazard Symbols T: Toxic
 

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