Pyrrolo[3,2-b]pyrrol-2(1H)-one,hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-[(2E)-1-oxo-4-(1-piperidinyl)-2-buten-1-yl]-,(3S,3aS,6aR)- (198062-54-3)

Identification
Name:	Pyrrolo[3,2-b]pyrrol-2(1H)-one,hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-[(2E)-1-oxo-4-(1-piperidinyl)-2-buten-1-yl]-,(3S,3aS,6aR)-
Synonyms:	Pyrrolo[3,2-b]pyrrol-2(1H)-one,hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-[(2E)-1-oxo-4-(1-piperidinyl)-2-butenyl]-,(3S,3aS,6aR)- (9CI); Pyrrolo[3,2-b]pyrrol-2(1H)-one,hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-[1-oxo-4-(1-piperidinyl)-2-butenyl]-,[3S-[3a,3aa,4(E),6ab]]-; GW 311616
CAS:	198062-54-3
Molecular Formula:	C19H31 N3 O4 S
Molecular Weight:	433.99
InChI:	InChI=1/C19H31N3O4S.ClH/c1-14(2)17-18-15(22(19(17)24)27(3,25)26)9-13-21(18)16(23)8-7-12-20-10-5-4-6-11-20;/h7-8,14-15,17-18H,4-6,9-13H2,1-3H3;1H/b8-7+;/t15-,17?,18-;/m1./s1
Molecular Structure:
Properties
Flash Point:	319.3°C
Boiling Point:	604.3°Cat760mmHg
Density:	g/cm³
Biological Activity:	Potent and selective inhibitor of human leukocyte elastase (HLE) (IC 50 = 22 nM); displays > 4500-fold selectivity over other human serine proteases. Orally active in vivo .
Flash Point:	319.3°C
Storage Temperature:	2-8°C
Safety Data
Hazard Symbols	Xi: Irritant