Identification |
Name: | 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide |
Synonyms: | 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide |
CAS: | 199666-03-0 |
Molecular Formula: | C17H15N3O6S2 |
Molecular Weight: | 0 |
InChI: | InChI=1/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19) |
Molecular Structure: |
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Properties |
Flash Point: | 333.3°C |
Boiling Point: | 627.4°C at 760 mmHg |
Density: | 1.471g/cm3 |
Refractive index: | 1.641 |
Biological Activity: | Potent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities. |
Flash Point: | 333.3°C |
Safety Data |
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