Elocalcitol (199798-84-0)

 Elocalcitol , its cas register number is 199798-84-0. The IPUAC name about this chemicals is (1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol .And it also can be called as Cyclohexanol, 3-((1-(5-ethyl-5-hydroxy-1-methyl-3-heptenyl)-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-5-fluoro-4-methylene-, (3aS-(1(1R*,3E),3aalpha,4E(1S*,3Z,5R*),7abeta))- and Cyclohexanol, 3-((2E)-((3aS,7aS)-1-((1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-heptenyl)-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-5-fluoro-4-methylene-, (1R,3Z,5S)- .

 Elocalcitol is a calcitriol analog for inhibition of prostate cell growth and in phase II clinical trial in patients with benign prostate hyperplasia (4/2004). It is an analogue of calcitriol that possesses the desirable properties of calcitriol but does not cause hypercalcemia and also Elocalcitol is in development for benign prostatic hyperplasia (BPH) and overactive bladder (OAB). However, Elocalcitol showed relevant effects on the symptomatic parameters urgency, frequency and nocturia, as well as on the urodynamic parameter maximum urinary flow rate (Qmax), this chemicals continues to show excellent safety and tolerability, avoiding the side effects associated with the currently available treatment options.

 This chemicals can be described computed from structure: 
1)InChI:
InChI=1/C29H43FO2/c1-6-29(32,7-2)17-8-10-20(3)25-14-15-26-22(11-9-16-28(25,26)5)12-13-23-18-24(31)19-27(30)21(23)4/h8,12-14,17,20,24,26-27,31-32H,4,6-7,9-11,15-16,18-19H2,1-3,5H3/b17-8+,22-12+,23-13+/t20-,24+,26-,27-,28+/m0/s1
2)Smiles:
[C@@H]1(C[C@@H](C(=C)/C(=C/C=C2/[C@H]3[C@](CCC2)(C(=CC3)[C@H](C/C=C/C(CC)(CC)O)C)C)C1)F)O