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5,27:13,18:21,24-Trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diium,6,12,19,20,25,26-hexahydro-, bromide (1:2) (199934-16-2)

Identification
Name:5,27:13,18:21,24-Trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diium,6,12,19,20,25,26-hexahydro-, bromide (1:2)
Synonyms:5,27:13,18:21,24-Trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diium,6,12,19,20,25,26-hexahydro-, dibromide (9CI); UCL 1684
CAS:199934-16-2
Molecular Formula: C34H30 N4 . 2 Br
Molecular Weight: 720.66
InChI: InChI=1/C34H28N4.2C2HF3O2/c1-3-10-33-29(8-1)31-16-18-37(33)23-27-6-5-7-28(20-27)24-38-19-17-32(30-9-2-4-11-34(30)38)36-22-26-14-12-25(13-15-26)21-35-31;2*3-2(4,5)1(6)7/h1-20H,21-24H2;2*(H,6,7)/b35-31+,36-32+;;
Molecular Structure: (C34H30N4.2Br) 5,27:13,18:21,24-Trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diium,...
Properties
Biological Activity: Highly potent, non-peptidic blocker of the apamin-sensitive Ca 2+ -activated K + channel (SK Ca ) (IC 50 = 3 nM in rat sympathetic neurons). Blocks hSK1 and rSK2 channels expressed in HEK 293 cells with IC 50 values of 762 and 364 pM respectively.
Color: white to off-white
Safety Data
 

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