| Identification | |
| Name: | Valinomycin |
| Synonyms: | 1,7,13,19,25,31-Hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone,3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl- (7CI);Cyclo(D-a-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-a-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-a-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl);NSC 122023;Valinomicin; |
| CAS: | 2001-95-8 |
| EINECS: | 217-896-6 |
| Molecular Formula: | C54H90 N6 O18 |
| Molecular Weight: | 1111.3218 |
| InChI: | InChI=1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66) |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 2811 6 |
| Density: | 1.060 |
| Refractive index: | 1.448 |
| Appearance: | White solid. |
| Specification: | white crystalline powder usageEng:K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction. Used as insecticid Safety Statements:36-45-36/37-28-37/39-26 36:Wear suitable protective clothing 45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 36/37:Wear suitable protective clothing and gloves 28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 37/39:Wear suitable protective clothing, gloves and eye/face protection 26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice |
| Report: |
EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory. |
| Packinggroup: | I |
| Biological Activity: | Selective K + ionophore (K 0.5 values are 48, 73, 75, 93 and 246 mM for K + , Rb + , Cs + , Na + and Li + respectively) that transports K + across biological and artificial lipid membranes. Inhibits Ca 2+ -ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro . |
| Storage Temperature: | 2-8°C |
| Color: | white |
| Usage: | K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction. Used as insecticid |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
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