Identification |
Name: | (S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine |
Synonyms: | Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, hydrochloride (1:2); |
CAS: | 213764-92-2 |
Molecular Formula: | C9H13Cl2IN2O |
Molecular Weight: | 363.03 |
InChI: | InChI=1/C9H11IN2O.2ClH/c10-7-3-9(5-11-4-7)13-6-8-1-2-12-8;;/h3-5,8,12H,1-2,6H2;2*1H/t8-;;/m0../s1 |
Molecular Structure: |
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Properties |
Flash Point: | 210.9°C |
Boiling Point: | 425.2°C at 760 mmHg |
Water Solubility: | Soluble to 100 mM in Water and to 100 mM in DMSO |
Biological Activity: | A highly potent and subtype-selective agonist for the α 4 β 2 and α 6 β 2 nicotinic acetylcholine receptors. Activates α -CTx-MII-sensitive and -insensitive components of [ 3 H]dopamine release from rat striatal synaptosomes, corresponding to α 6 β 2 and α 4 β 2 (EC 50 values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over α 3 β 4, α 7 and muscle nAChR receptors respectively. |
Flash Point: | 210.9°C |
Safety Data |
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