2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide (22503-72-6)

Identification
Name:	2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-methyl-, 1,1-dioxide
Synonyms:	IDRA 21
CAS:	22503-72-6
Molecular Formula:	C8H9 Cl N2 O2 S
Molecular Weight:	232.69
InChI:	InChI=1/C8H9ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-5,10-11H,1H3/t5-/m1/s1
Molecular Structure:
Properties
Flash Point:	198.8°C
Boiling Point:	405.1°Cat760mmHg
Density:	1.394g/cm³
Refractive index:	1.571
Biological Activity:	Inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. More able to cross the blood-brain barrier than cyclothiazide (6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide ).
Flash Point:	198.8°C
Safety Data

Other Product

2H-1,2,4-Benzothiadiazine,7-chloro-3-(4-methyl-1-piperazinyl)-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-2-methyl-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-carboxaldehyde,3-[1,2-dihydro-4-hydroxy-1-(3-methylbutyl)-2-oxo-3-quinolinyl]-,1,1-dioxide
7-Chloro-4-methyl-3-(4-methyl-1-piperazinyl)-4H-1,2,4-benzothiadiazine 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(2-methylpropyl)-, 1,1,-dioxide, mixt. with 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2,3,6-trimethylphenyl acetate
Butanamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)-, mixt. with 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-[(4-fluorophenyl)methyl]-3,4-dihydro-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-(1-phenylethyl)-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-[(2,5-dioxo-1-pyrrolidinyl)methyl]-3,4-dihydro-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[2-[2-(1-phthalazinyl)hydrazinylidene]propyl]-,1,1-dioxide
Spiro[2H-1,2,4-benzothiadiazine-3(4H),4'-piperidine]-7-sulfonamide,6-chloro-1'-ethyl-, 1,1-dioxide, hydrochloride (1:1)
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(1-phenylethyl)-, 1,1-dioxide, mixt. with ((2,3-dihydro-1,4-benzodioxin-6-yl)methyl)guanidine sulfate (2:1)
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide, compd. with 3-[[6-O-(6-deoxy-α-l-mannopyranosyl)-β-d-glucopyranosyl]oxy]-6-[(diethylamino)methyl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one (1:1)
2H-1,2,4-Benzothiadiazine-7-sulfonamide,3,4-dihydro-2-methyl-3-[2-[2-(1-phthalazinyl)hydrazinylidene]propyl]-6-(trifluoromethyl)-,1,1-dioxide
4H-1,2,4-Benzothiadiazine, 3-chloro-4-(1-methylethyl)-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-carboxamide,3-[1-(2-cyclopropylethyl)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]-N-[3-(1H-imidazol-1-yl)propyl]-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-carboxamide,3-[1-(2-cyclopropylethyl)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]-N-[2-(4-methoxyphenyl)ethyl]-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-carboxamide,3-[1-(2-cyclopropylethyl)-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]-N-[3-(diethylamino)propyl]-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine-7-carboxamide,3-[1,2-dihydro-4-hydroxy-1-(3-methylbutyl)-6-nitro-2-oxo-3-quinolinyl]-,1,1-dioxide