| Identification | |
| Name: | 2H-1,2,4-Benzothiadiazine-7-sulfonamide,3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide |
| Synonyms: | 2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-, 1,1-dioxide (6CI,7CI,8CI);6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide;6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide;6-Chloro-3-(5-bicyclo[2.2.1]hept-2-enyl)-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-(5-norbornen-2-yl)-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide;Anhydron; Aquirel; Cyclothiazide; Doburil; Fluidil; Lilly 35483; MDi 193;Renazide; Valmiran |
| CAS: | 2259-96-3 |
| EINECS: | 218-859-7 |
| Molecular Formula: | C14H16 Cl N3 O4 S2 |
| Molecular Weight: | 389.8775 |
| InChI: | InChI=1/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)/t7-,8+,9?,14?/m0/s1 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 234 DEG C |
| Density: | 1.572 g/cm3 |
| Refractive index: | 1.653 |
| Water Solubility: | Soluble in Methanol and Ethanol |
| Solubility: | Soluble in Methanol and Ethanol |
| Appearance: | White Solid |
| Biological Activity: | Positive allosteric modulator of AMPA receptors that potently inhibits AMPA receptor desensitization. Selective for the flip variant of each of the four receptor subunits. Also available as part of the AMPA Receptor Tocriset™ . |
| Storage Temperature: | 2-8°C |
| Color: | CRYSTALS FROM DILUTE ALCOHOL WHITE TO NEARLY WHITE POWDER |
| Safety Data | |
| Hazard Symbols |
Xi: Irritant
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