| Identification | |
| Name: | 2,9-Dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione,4-ethylidene-7-hydroxy-6,7,14-trimethyl-, (1R,4Z,6R,7R)- |
| Synonyms: | 2,3,5,7a-Tetrahydro-1,7a-dihydroxy-7-(hydroxymethyl)-4-methyl-1H-pyrroliziniumhydroxide, inner salt, cyclic diester with senecic acid (7CI);4,8-Secosenecionan-8,11,16-trione, 12-hydroxy-4-methyl-;2,9-Dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione,4-ethylidene-7-hydroxy-6,7,14-trimethyl-, [1R-(1R*,4Z,6R*,7R*)]-; NSC 89945;Renardin; Renardine; Renardine (neutral); Senkirkin; Senkirkine; Senkirkine(neutral) |
| CAS: | 2318-18-5 |
| Molecular Formula: | C19H27 N O6 |
| Molecular Weight: | 366.48 |
| InChI: | InChI=1/C19H27NO6/c1-5-13-10-12(2)19(3,24)18(23)25-11-14-6-8-20(4)9-7-15(16(14)21)26-17(13)22/h5-6,12,15,24H,7-11H2,1-4H3/b13-5u,14-6- |
| Molecular Structure: |  |
| Properties | |
| Transport: | 1544 |
| Flash Point: | 319.6°C |
| Boiling Point: | 604.9°Cat760mmHg |
| Density: | 1.22g/cm3 |
| Refractive index: | 1.546 |
| Solubility: | Readily soluble in ethyl acetate and chloroform; less soluble in water, ethanol, acetone and benzene In water, 8.6X10+4 mg/L @ 25 deg C /Estimated/ |
| Specification: | usageEng:Senkirkine is a hepatotoxic pyrrolizidine alkaloid. Studies show that Senkirkine has carincogenic activity as it induced chromosomal aberrations in cultured mammalian cells as well as hepatic tumors in rats. |
| Packinggroup: | III |
| Flash Point: | 319.6°C |
| Usage: | Senkirkine is a hepatotoxic pyrrolizidine alkaloid. Studies show that Senkirkine has carincogenic activity as it induced chromosomal aberrations in cultured mammalian cells as well as hepatic tumors in rats. |
| Safety Data | |
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