Urea,N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-, hydrochloride (1:1) (249889-64-3)

Identification
Name:	Urea,N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-, hydrochloride (1:1)
Synonyms:	Urea,N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-, monohydrochloride (9CI);SB 334867; SB 334867A
CAS:	249889-64-3
Molecular Formula:	C17H13 N5 O2 . Cl H
Molecular Weight:	319.32
Molecular Structure:
Properties
Biological Activity:	Selective non-peptide orexin OX 1 receptor antagonist. pK b values are 7.2 and < 5 for inhibition of intracellular Ca 2+ release in CHO cells expressing human OX 1 and OX 2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo .
Safety Data

Other Product

Urea,N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-
Urea,N-[5-(1,1-dimethylethyl)-7-benzoxazolyl]-N'-[4-[6-(4-morpholinylmethyl)-3-pyridinyl]-1-naphthalenyl]-
Urea,N-(7-chloro-1,4-dihydro-5-methyl-4-oxo-1-phenyl-1,8-naphthyridin-2-yl)-N'-(4-fluorophenyl)-N-phenyl-
Cyclobutanecarboxamide,N-[2-[[1-[(4-ethoxy-2,3-dihydro-2-oxo-6-benzoxazolyl)methyl]-4-piperidinyl]amino]-5-benzoxazolyl]-
Urea,N,N-dimethyl-N'-(6-methyl-1H-benzimidazol-2-yl)-, hydrochloride (1:1)
1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea
1,6-Naphthyridin-5(6H)-one,2-[4-[[4-(2-benzoxazolyl)-1-piperidinyl]methyl]phenyl]-3-phenyl-
Urea,N-[2-[4-[3-(4-fluorophenyl)-5-methyl-1H-indol-1-yl]-1-piperidinyl]ethyl]-N,N'-dimethyl-, hydrochloride
Urea,N-methyl-N'-[6-[2-(1-piperidinyl)ethoxy]-5-benzofuranyl]-, hydrochloride (1:1)
4-Piperidinecarboxamide,1-[2-(1,3-benzodioxol-5-yl)ethyl]-N-(6-methoxy-1,5-naphthyridin-4-yl)-4-methyl-
1H-Imidazole-4-sulfonamide,N-[2-[[1-[(4-ethoxy-2,3-dihydro-2-oxo-6-benzoxazolyl)methyl]-4-piperidinyl]amino]-5-benzoxazolyl]-1-methyl-
Urea,N-[2-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl]-1,1-dimethylethyl]-N'-(1-methylethyl)-
Benzamide,N-[8-[4-(2-hydroxyethyl)-1-piperazinyl]-1,7-naphthyridin-6-yl]-4-methyl-
Urea,N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]-N'-[4-[(diethylamino)methyl]-2,6-bis(1-methylethyl)phenyl]-
Urea,N-[1-butyl-1,2-dihydro-4-(3-methoxyphenyl)-2-oxo-1,8-naphthyridin-3-yl]-N'-[4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,6-bis(1-methylethyl)phenyl]-
Urea,N,N'-bis(4-amino-2-methyl-6-quinolinyl)-, hydrochloride (1:2)
Urea,N-[3-(4-amino-2-propyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)propoxy]-N'-(4-methylphenyl)-, trifluoroacetate
Urea,N-[3-(4-amino-2-propyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)propoxy]-N'-(2-phenylethyl)-, trifluoroacetate
Benzenamine,N,N-dimethyl-4-[[4-[[4'-(5-methyl-2-benzoxazolyl)[1,1'-biphenyl]-4-yl]azo]-1-naphthalenyl]azo]-
Acetamide,N-[(3R)-1-[(6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-2-[1-[(2-methyl-5-benzoxazolyl)carbonyl]-4-piperidinylidene]-