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Benzamide,4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]- (251456-60-7)

Identification
Name:Benzamide,4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-
Synonyms:MS 344;M 344 (enzyme inhibitor);
CAS:251456-60-7
Molecular Formula: C16H25N3O3
Molecular Weight: 307.39
InChI: InChI=1/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20)
Molecular Structure: (C16H25N3O3) MS 344;M 344 (enzyme inhibitor);
Properties
Density:1.137g/cm3
Refractive index:1.558
Biological Activity: Histone deacetylase inhibitor (IC 50 = 100 nM). Induces terminal cell differentiation and causes an increase in hyperacetylated histone H4. Antiproliferative agent; suppresses the growth of human endometrial and ovarian cancer cells by inducing cell cycle arrest and apoptosis.
Storage Temperature: 2-8°C
Safety Data