| Identification | |
| Name: | 1H-Imidazole,1-[2-(trifluoromethyl)phenyl]- |
| Synonyms: | Imidazole,1-(a,a,a-trifluoro-o-tolyl)- (8CI);1-[2-(Trifluoromethyl)phenyl]-1H-imidazole; |
| CAS: | 25371-96-4 |
| EINECS: | -0 |
| Molecular Formula: | C10H7F3N2 |
| Molecular Weight: | 212.1713 |
| InChI: | InChI=1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H |
| Molecular Structure: | ![(C10H7F3N2) Imidazole,1-(a,a,a-trifluoro-o-tolyl)- (8CI);1-[2-(Trifluoromethyl)phenyl]-1H-imidazole;](https://img.guidechem.com/casimg/25371-96-4.gif) |
| Properties | |
| Density: | 1.27 g/cm3 |
| Refractive index: | 1.522 |
| Water Solubility: | Soluble in DMSO (30mg/ml) or dichloromethane (25%); slightly soluble in water (5mg/ml), 0.1 N HCl (6mg/ml) or 0.1 N NaOH (2mg/ml). |
| Solubility: | Soluble in DMSO (30mg/ml) or dichloromethane (25%); slightly soluble in water (5mg/ml), 0.1 N HCl (6mg/ml) or 0.1 N NaOH (2mg/ml). |
| Appearance: | White solid. |
| Specification: |
1H-Imidazole,1-[2-(trifluoromethyl)phenyl]- , its cas register number is 25371-96-4. It also can be called 1-(2-(Trifluoromethyl)phenyl)-1H-imidazole ; and 1-(2-Trifluoromethylphenyl)imidazole . |
| Biological Activity: | A potent inhibitor of neuronal and inducible NO synthases, with much lower affinity for the endothelial isoform (displays IC 50 values of 28.2, 27.0 and 1057.5 μ M respectively). Antinociceptive in vivo . |
| Storage Temperature: | 2-8°C |
| Sensitive: | Light Sensitive |
| Safety Data | |
| Hazard Symbols |
Xi: Irritant
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