Identification |
Name: | 1H-Isoindole-1,3(2H)-dione,2-[(3R)-2,6-dioxo-3-piperidinyl]- |
Synonyms: | 1H-Isoindole-1,3(2H)-dione,2-(2,6-dioxo-3-piperidinyl)-, (R)-; Phthalimide, N-(2,6-dioxo-3-piperidyl)-,D-(+)- (8CI); (+)-(R)-Thalidomide; (+)-Thalidomide; (R)-(+)-Thalidomide;(R)-Thalidomide; NSC 91729; R-(D)-Thalidomide |
CAS: | 2614-06-4 |
Molecular Formula: | C13H10 N2 O4 |
Molecular Weight: | 258.25 |
InChI: | InChI=1/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)/t9-/m1/s1 |
Molecular Structure: |
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Properties |
Flash Point: | 262.1°C |
Boiling Point: | 509.7°C at 760 mmHg |
Density: | 1.503g/cm3 |
Refractive index: | 1.646 |
Solubility: | Sparingly soluble in methanol, ethanol, acetone, ethyl acetate, butyl acetate, glacial acetic acid. Very soluble in dioxane, DMF, pyridine. Practically insoluble in ether, chloroform, benzene. In water, 45-60 mg/l @ 25 deg C. |
Specification: |
(+)-Thalidomide with cas registry number of 2614-06-4 is also known as 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)- ; D-Thalidomide ; NSC 91729 ; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, (+)- ; R-(+)-Thalidomide ; d-Thalidomide ; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)- (9CI) ; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)- . It is optically active isomer of Thalidomide , which inhibits FGF-induced angiogenesis and replication of human immunodeficiency virus type 1.
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Flash Point: | 262.1°C |
Storage Temperature: | -20?C Freezer |
Color: | white |
Usage: | Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative |
Safety Data |
Hazard Symbols |
T: Toxic
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