| Identification | |
| Name: | [1,2,4]Triazolo[1,5-a]pyrimidin-5(4H)-one,2-amino-6-methyl-4-propyl- |
| Synonyms: | s-Triazolo[1,5-a]pyrimidin-5(4H)-one,2-amino-6-methyl-4-propyl- (8CI); 2-Amino-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2-Amino-6-methyl-4-propyl-s-triazolo[1,5-a]pyrimid-5(4H)-one;2-Amino-6-methyl-5-oxo-4-propyl-4,5-dihydro-s-triazolo[1,5-a]pyrimidine; ICI63197 |
| CAS: | 27277-00-5 |
| EINECS: | 248-383-5 |
| Molecular Formula: | C9H13 N5 O |
| Molecular Weight: | 207.23242 |
| InChI: | InChI=1S/C9H13N5O/c1-3-4-13-7(15)6(2)5-14-9(13)11-8(10)12-14/h5H,3-4H2,1-2H3,(H2,10,12) |
| Molecular Structure: | ![(C9H13N5O) s-Triazolo[1,5-a]pyrimidin-5(4H)-one,2-amino-6-methyl-4-propyl- (8CI); 2-Amino-6-methyl-4-propyl-4H-...](https://img.guidechem.com/structureimg/27277-00-5.gif) |
| Properties | |
| Transport: | 2811 |
| Melting Point: | 161.8-163 °C |
| Flash Point: | 231.9°C |
| Boiling Point: | 459.9°C at 760 mmHg |
| Density: | 1.44g/cm3 |
| Refractive index: | 1.696 |
| Water Solubility: | DMSO: 13 mg/mL |
| Solubility: | DMSO: 13 mg/mL |
| Appearance: | White solid |
| Specification: |
[1,2,4]Triazolo[1,5-a]pyrimidin-5(4H)-one,2-amino-6-methyl-4-propyl- (CAS NO.27277-00-5) is also called as Ici 63197 ; 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo-(1,5-A)- pyrimidin-5-one ; Caswell No. 033E ; EINECS 248-383-5 ; PP 769 ; 2-Amino-6-methyl-4-propyl-1,2,4-triazolo(1,5-a)pyrimidin-5(4H)-one ; 2-Amino-6-methyl-5-oxo-4n-propyl-4,5-dihydro-s-triazolo(1,5-a)pyrimidine ; 2-Amino-4,5-dihydro-6-methyl-4-propyl-5-triazolo-(1,5-c)-pyramidin-5-one . |
| Packinggroup: | III |
| Biological Activity: | Potent phosphodiesterase (PDE) 4 inhibitor (IC 50 = 35 nM for inhibition of [ 3 H]-rolipram binding to rat brain). Antidepressant following systemic administration in vivo . |
| Flash Point: | 231.9°C |
| Color: | white |
| Safety Data | |
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