| Identification |
| Name: | 1H-Imidazolium,1-hexadecyl-2-methyl-3-(phenylmethyl)-, iodide (1:1) |
| Synonyms: | 1H-Imidazolium,1-hexadecyl-2-methyl-3-(phenylmethyl)-, iodide (9CI); NH 125 |
| CAS: | 278603-08-0 |
| Molecular Formula: | C27H45 N2 . I |
| Molecular Weight: | 524.56 |
| InChI: | InChI=1/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1 |
| Molecular Structure: |
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| Properties |
| Melting Point: | 88.2-94.9 °C
|
| Biological Activity: | Histidine protein kinase and eukaryotic elongation factor 2 (eEF-2) kinase (CaMK III) inhibitor (IC 50 = 60 nM) that displays 125-fold, > 1300-fold and > 1500-fold selectivity over PKC, PKA and CaMK II respectively. Exhibits anticancer activity in a variety of malignant cell lines (IC 50 values are 0.7 - 4.8 μ M) and blocks G 1 /S cell cycle progression. Also is an effective antibacterial agent in vitro (IC 50 = 6.6 μ M) and in vivo . |
| Storage Temperature: | −20°C |
| Safety Data |
| Hazard Symbols |
Xi: Irritant
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