| Identification | |
| Name: | Estra-1,3,5(10)-triene-3,17-diol(17b)-,3-[bis(2-chloroethyl)carbamate] |
| Synonyms: | Estradiol,3-[bis(2-chloroethyl)carbamate] (7CI,8CI); Carbamic acid, bis(2-chloroethyl)-,17b-hydroxyestra-1,3,5(10)-trien-3-ylester (8CI); 17b-Estradiol3-[bis(2-chloroethyl)carbamate]; Estracty; Estradiol3-[N,N-bis(2-chloroethyl)carbamate]; Estramustine; Leo 275; NSC 89201; Ro22-2296/000 |
| CAS: | 2998-57-4 |
| EINECS: | 221-076-3 |
| Molecular Formula: | C23H31 Cl2 N O3 |
| Molecular Weight: | 440.45 |
| InChI: | InChI=1/C23H31Cl2NO3/c1-23-9-8-18-17-5-3-16(29-22(28)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)27/h3,5,14,18-21,27H,2,4,6-13H2,1H3/t18-,19-,20+,21+,23+/m1/s1 |
| Molecular Structure: | ![(C23H31Cl2NO3) Estradiol,3-[bis(2-chloroethyl)carbamate] (7CI,8CI); Carbamic acid, bis(2-chloroethyl)-,17b-hydroxye...](https://img1.guidechem.com/chem/e/dict/110/2998-57-4.jpg) |
| Properties | |
| Melting Point: | 104 - 105 |
| Flash Point: | 296°C |
| Boiling Point: | 565.8°C at 760 mmHg |
| Density: | 1.253 g/cm3 |
| Refractive index: | 1.576 |
| Solubility: | Insoluble |
| Specification: |
Estramustine is marketed in the United States by Pharmacia (now a subsidiary of Pfizer).It is a derivative of estrogen (specifically, estradiol) with an nitrogen mustard-carbamate ester moiety that makes it a alkylating antineoplastic agent similar to mechlorethamine, with estrogen-induced specificity. |
| Flash Point: | 296°C |
| Storage Temperature: | Store in original container in a cool dark place. |
| Usage: | Antineoplastic. |
| Safety Data | |
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