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L-Proline,4-hydroxy-1-nitroso-, (4R)- (30310-80-6)

Identification
Name:L-Proline,4-hydroxy-1-nitroso-, (4R)-
Synonyms:L-Proline,4-hydroxy-1-nitroso- (6CI); L-Proline, 4-hydroxy-1-nitroso-, trans-;N-Nitroso-4-hydroxyproline; N-Nitrosohydroxyproline
CAS:30310-80-6
Molecular Formula: C5H8 N2 O4
Molecular Weight: 160.15
InChI: InChI=1/C5H8N2O4/c8-3-1-4(5(9)10)7(2-3)6-11/h3-4,8H,1-2H2,(H,9,10)/t3-,4+/m1/s1
Molecular Structure: (C5H8N2O4) L-Proline,4-hydroxy-1-nitroso- (6CI); L-Proline, 4-hydroxy-1-nitroso-, trans-;N-Nitroso-4-hydroxypro...
Properties
Flash Point: 245.7°C
Boiling Point: 482.7°Cat760mmHg
Density:1.79g/cm3
Refractive index:1.674
Specification:

  trans-4-Hydroxy-1-nitroso-l-proline (CAS NO.30310-80-6), an important component of collagen, was transformed into its N-nitroso-derivative, (4R)-4-hydroxy-1-nitroso-l-proline, 1 by butylnitrite in the acidic medium. The structure is a cyclic hydroxy-N-nitrosoacid with the carboxyl and hydroxyl groups trans to each other.

Report:

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 , 1978,p. 303.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Flash Point: 245.7°C
Safety Data