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2-Propenamide,2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl- (304896-28-4)
Identification
Name:
2-Propenamide,2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-
Synonyms:
AGK 2
CAS:
304896-28-4
Molecular Formula:
C23H13 Cl2 N3 O2
Molecular Weight:
0
Molecular Structure:
Properties
Biological Activity:
Selective inhibitor of SIRT2 (IC 50 = 3.5 μ M). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 μ M. Reduces α -synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease.
Storage Temperature:
Room temp
Safety Data
Hazard Symbols
Xi: Irritant
Other Product
2-Propenamide,2-cyano-N-(3,4-dichlorophenyl)-3-[5-(diethylamino)-2-furanyl]-
2-Propenamide, 2-cyano-3-[5-(dimethylamino)-2-furanyl]-
2-Propenamide, 3-[4-bromo-5-(dimethylamino)-2-furanyl]-2-cyano-N,N-dimethyl-
2-Propenamide, 2-cyano-3-[5-(dimethylamino)-2-furanyl]-N-(2-fluorophenyl)-
2-Propenamide, 2-cyano-3-[5-(dimethylamino)-2-furanyl]-N-(2-furanylmethyl)-
2-Propenamide,2-cyano-3-[5-(diethylamino)-2-furanyl]-N-(2-fluorophenyl)-
2-Propenamide, 3-[4-bromo-5-(dimethylamino)-2-furanyl]-2-cyano-N-(2-methylphenyl)-
2-Propenamide, 2-cyano-3-(8-hydroxy-5-quinolinyl)-N-phenyl-
2-Propenamide, N-(3-chlorophenyl)-2-cyano-3-[5-(diethylamino)-2-furanyl]-
2-Propenamide, 2-cyano-3-[5-(dimethylamino)-2-furanyl]-N-(3-methylphenyl)-
2-Propenamide, 2-cyano-3-[5-(diethylamino)-2-furanyl]-N-(3-methylphenyl)-
2-Propenamide,2-cyano-3-[5-(dimethylamino)-2-furanyl]-N-[3-(1-methylethoxy)phenyl]-
2-Propenamide, 3-[4-bromo-5-(dimethylamino)-2-furanyl]-N-(3-bromophenyl)-2-cyano-
2-Propenamide, 2-cyano-3-[5-(diethylamino)-2-furanyl]-N-(3,4-dimethylphenyl)-
2-Propenamide, 2-cyano-3-[5-(diethylamino)-2-furanyl]-N-phenyl-
2-Propenamide, N-(4-bromophenyl)-2-cyano-3-[5-(dimethylamino)-2-furanyl]-
2-Propenamide, N-(4-bromophenyl)-2-cyano-3-[5-(diethylamino)-2-furanyl]-
2-Propenamide, 2-cyano-3-[5-(dimethylamino)-2-furanyl]-N-(4-ethoxyphenyl)-
2-Propenamide,2-cyano-3-[5-(diethylamino)-2-furanyl]-N-(2,4-dimethylphenyl)-
2-Propenamide,2-cyano-3-[5-(diethylamino)-2-furanyl]-N-(4-fluorophenyl)-
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