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2-Propenamide,2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl- (304896-28-4)

Identification
Name:2-Propenamide,2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-
Synonyms:AGK 2
CAS:304896-28-4
Molecular Formula: C23H13 Cl2 N3 O2
Molecular Weight: 0
Molecular Structure: (C23H13Cl2N3O2) AGK 2
Properties
Biological Activity: Selective inhibitor of SIRT2 (IC 50 = 3.5 μ M). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 μ M. Reduces α -synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease.
Storage Temperature: Room temp
Safety Data
Hazard Symbols Xi: Irritant