| Identification | |
| Name: | Chlorambucil |
| Synonyms: | 4-(p-bis(2-chloroethyl)aminophenyl)butyric acid; 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid; 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid; 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)butyric acid; 4-[bis(2-chloroethyl)amino]benzenebutanoic acid; 4-[Bis(2-chloroethyl)aminophenyl]butyric acid; Ambochlorin; Amboclorin; cb 1348; Cb l348; Chloroambucil; Chloraminophen; Chlorobutin; Ecloril; Elcoril; Leukersan; Leukoran; Linfolizin; Linfolysin; N,N-Di-(2-chloroethyl)-gamma-(p-aminophenyl)butyric acid; Phenylbutyric acid nitrogen mustard; gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid |
| CAS: | 305-03-3 |
| EINECS: | 206-162-0 |
| Molecular Formula: | C14H19Cl2NO2 |
| Molecular Weight: | 304.21 |
| InChI: | InChI=1/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19) |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 2811 |
| Flash Point: | 232.1 ºC |
| Boiling Point: | 460.1 ºC at 760 mmHg |
| Density: | 1.248 g/cm3 |
| Stability: | Stable, but may be light sensitive. Store cold. Incompatible with strong oxidizing agents. |
| Refractive index: | 1.536 |
| Solubility: | <0.01 g/100 mL at 22 ºC |
| Appearance: | beige powder |
| Specification: |
Chlorambucil (CAS NO.305-03-3) is a white to pale beige crystalline or granular powder with a slight odor. And it is a chemotherapy drug , also it insoluble in water.It is an alkylating agent. |
| Report: |
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 144.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 , 1975,p. 125.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 , 1981,p. 115.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 , 1981,p. 115.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 , 1975,p. 125.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. |
| Packinggroup: | III |
| Flash Point: | 232.1 ºC |
| Storage Temperature: | 2-8°C |
| Color: | OFF-WHITE, SLIGHTLY GRANULAR POWDER Flattened needles from petroleum ether Fine white crystals |
| Usage: | Medication (vet). |
| Safety Data | |
| Hazard Symbols |
T:Toxic
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