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Aristolochic acid I (313-67-7)

Identification
Name:Aristolochic acid I
Synonyms:-
CAS:313-67-7
EINECS: 206-238-3
Molecular Formula: C17H11NO7
Molecular Weight: 341.27174
InChI: InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20)
Molecular Structure: (C17H11NO7) -
Properties
Transport:UN 1544
Melting Point: 260 oC
Flash Point: 326 oC
Boiling Point: 615.5 oC at 760 mmHg
Density:1.571g/cm3
Stability:Stable at room temperature in closed containers under normal storage and handling conditions.
Water Solubility:DMSO: soluble in water
Solubility:DMSO: soluble in water
Appearance:Yellow powder
Specification:

 Aristolochic acid (CAS NO.313-67-7) is composed of a ~1:1 mixture of two forms, aristolochic acid I and aristolochic acid II ,and is a rodent carcinogen found in Aristolochia and Asarum, both in the Aristolochiaceae family of plants.In addition to its carcinogenicity, it is also highly nephrotoxic and may be a causative agent in Balkan nephropathy.
It is hazardous,so the first aid measures and others should be known.Such as: When on the skin: first,should  flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing. Secondly,Get shoesmedical aid . Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.
In addition, Aristolochic acid (CAS NO.313-67-7) is not compatible with strong oxidizing agents,  strong bases, alkalies,and you must not take it with excess heat, direct sunlight and incompatible materials.And also prevent it to broken down into hazardous decomposition products: oxides of nitrogen,carbon dioxide,carbon monoxide.

Packinggroup: III
Flash Point: 326 oC
Color: yellow
Usage:

 Aristolochic acid (CAS NO.313-67-7) still is present sometimes in herbal remedies (such as for weight loss), primarily because of substitution of innocuous herbs with Aristolochia species.

Safety Data
Hazard Symbols T:Toxic