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1-Piperazineaceticacid, 4-(phenylmethyl)-,2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide (315183-21-2)

Identification
Name:1-Piperazineaceticacid, 4-(phenylmethyl)-,2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide
Synonyms:1-Piperazineaceticacid, 4-(phenylmethyl)-, [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide(9CI)
CAS:315183-21-2
Molecular Formula: C23H28 N4 O2
Molecular Weight: 0
InChI: InChI=1/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+
Molecular Structure: (C23H28N4O2) 1-Piperazineaceticacid, 4-(phenylmethyl)-, [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide(9CI)
Properties
Flash Point: °C
Boiling Point: °Cat760mmHg
Density:g/cm3
Biological Activity: Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC 50 = 0.22 μ M). Also activates procaspase-7 in a less efficient manner (EC 50 = 4.5 μ M). Pro-apoptotic; induces apoptosis in both cancerous and non-cancerous cells dependent on procaspase-3 concentration (IC 50 values are 0.003-1.41 and 5.02-9.98 μ M respectively).
Flash Point: °C
Safety Data
 

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