| Identification |
| Name: | 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID |
| Synonyms: | BIBR 1532; |
| CAS: | 321674-73-1 |
| Molecular Formula: | C21H17NO3 |
| Molecular Weight: | 331.36 |
| InChI: | InChI=1/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+ |
| Molecular Structure: |
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| Properties |
| Flash Point: | 317.036°C |
| Boiling Point: | 600.607°C at 760 mmHg |
| Density: | 1.285g/cm3 |
| Refractive index: | 1.698 |
| Biological Activity: | Selective telomerase inhibitor (IC 50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest. |
| Flash Point: | 317.036°C |
| Safety Data |
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