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2-Thiopheneacetic acid,5-benzoyl-a-methyl- (33005-95-7)

Identification
Name:2-Thiopheneacetic acid,5-benzoyl-a-methyl-
CAS:33005-95-7
EINECS: 251-329-3
Molecular Formula: C14H12O3S
Molecular Weight: 260.32
InChI: InChI=1/C14H12O3S/c1-9(14(16)17)11-7-8-12(18-11)13(15)10-5-3-2-4-6-10/h2-9H,1H3,(H,16,17)
Molecular Structure: (C14H12O3S) (RS)-Tiaprofenicacid;(?à)-Tiaprofenic acid;FC 3001;RU15060;Suralgan;Surgam;Tiaprofen;Tiaprofenic ac...
Properties
Flash Point: 226.1ºC
Boiling Point: 450.3ºC at 760 mmHg
Density:1.29 g/cm3
Refractive index:1.612
Specification:

Usage and dosage: intramuscular injection: 0.2 ~ 0.4g / d, according to the disease, up to 0.6 / d. Oral: 0.6g / d, min 2 to 3 doses. Patients with renal insufficiency, where appropriate dose was reduced to 0.2g / times, 2 times / d.
Pharmacological effects: Surgam (33005-95-7) has effects of antipyretic, analgesic and anti-inflammatory , can reduce swelling, relieve joint stiffness. Relieve pain, improve joint movement.
Mechanism :Surgam (33005-95-7) is the inhibition of prostaglandin synthesis,play a role on blocking inflammatory mediators.
Adverse reactions: rare adverse reactions, manifested as nausea, vomiting, stomach pain, diarrhea, constipation. Also appear sleepiness, fatigue, headache and skin reactions such as rash, itching, dry skin breakdowns.

Flash Point: 226.1ºC
Safety Data