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Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11b)- (338-98-7)

Identification
Name:Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11b)-
Synonyms:Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-, 21-acetate(6CI,7CI,8CI);21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-diene-3,20-dione;9-Fluoro-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione21-acetate;9-Fluoroprednisolone 21-acetate;9-Fluoroprednisolone acetate;9a-Fluoro-11b,17a,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate;9a-Fluoroprednisolone 21-acetate;9a-Fluoroprednisolone acetate;Predef;Predef R 2X;
CAS:338-98-7
EINECS: 206-423-9
Molecular Formula: C23H29FO6
Molecular Weight: 420.47
InChI: InChI=1/C23H29FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h6,8,10,16-18,27,29H,4-5,7,9,11-12H2,1-3H3
Molecular Structure: (C23H29FO6) Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-, 21-acetate(6CI,7CI,8CI);21-Acetoxy-9-flu...
Properties
Flash Point: 302.5 °C
Boiling Point: 576.5 °Cat760mmHg
Density:1.32 g/cm3
Refractive index:1.577
Specification:

The IUPAC name of Isoflupredone acetate is [2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate . With the CAS registry number 338-98-7, it is also named as 9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate ; 9-Fluoroprednisolone 21-acetate ; 9-Fluoroprednisolone acetate ; 9-Fluorprednisolone acetate ; 9alpha-Fluoroprednisolone acetate ; Isoflupredone 21-acetate ; NSC 37977 ; Predef ; Predef (Veterinary) ; Predef 2X ; Prednisolone, 9-fluoro-, 21-acetate ; U 6013 ; UNII-55P9TUL75S ; Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11beta)- ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-, 21-acetate ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-, 21-acetate (8CI) . The product's classification code are anti-inflammatory, hormone and reproductive effect.

 Isoflupredone acetate is pharmaceutical raw materials and intermediates. It also can be used in clinical treatment. Scientist have done a lot of experiments to confirm the following result. Hypokalemia should be considered in the differential diagnosis for cows that are weak or recumbent, particularly after treatment for ketosis with isoflupredone acetate.

 Isoflupredone acetate is 14 times as potent as hydrocortisone as an anti-inflammatory steroid as measured by the cotton pellet implantation assay which has been reported by research workers. Isoflupredone acetate markedly inhibits inflammatory reaction through its controlling influence on connective tissue and vascular components. Topically applied isoflupredone acetate is rapidly effective. The inflammatory response may also be effectively inhibited by isoflupredone acetate In ulcerations of the ear flaps, irritated lesions of the skin, and otitis externa, wounds of the concha. Chronic conditions respond more slowly and relapses are more frequent.

Flash Point: 302.5 °C
Safety Data
 

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