Ethanone,1-(4-fluorophenyl)-2-phenyl- (347-84-2)

The 1-(4-Fluorophenyl)-2-phenylethanone with cas registry number of 347-84-2 is also known as 4'-Fluoro-2-phenylacetophenone. It is a kind of pharmaceticals. Both its systematic name and IUPAC name are the same which is called 1-(4-fluorophenyl)-2-phenylethanone.

The physical properties about this chemical are: (1)ACD/LogP: 3.23; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 3; (6)Index of Refraction: 1.567; (7)Molar Refractivity: 60.76 cm³; (8)Molar Volume: 185.8 cm³; (9)Surface Tension: 41.4 dyne/cm; (10)Density: 1.152 g/cm³; (11)Flash Point: 137.9 °C; (12)Enthalpy of Vaporization: 57.57 kJ/mol; (13)Boiling Point: 332.9 °C at 760 mmHg; (14)Vapour Pressure: 0.000141 mmHg at 25°C.

Preparation: this chemical can be made by reaction of phenylacetyl chloride with fluorobenzene. In this process, you also need reagents: AlCl₃ and carbon disulfide.

Uses of 1-(4-Fluorophenyl)-2-phenylethanone: it is used for the synthesis of 1-(4-Fluorphenyl)-2-phenyl-1-ethanon-p-tolylsulfonylhydrazon together with 4-fluoro-deoxybenzoin. The reaction will need solvent Ethanol with 77% yield. The reaction time is 3 hours.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. Therefore, wear suitable protective clothing, gloves and eye/face protection during using it. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(c1ccc(F)cc1)Cc2ccccc2;
(2)InChI: InChI=1/C14H11FO/c15-13-8-6-12(7-9-13)14(16)10-11-4-2-1-3-5-11/h1-9H,10H2;
(3)InChIKey: YFYKGCQUWKAFLW-UHFFFAOYAO