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9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE (3519-82-2)

Identification
Name:9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE
Synonyms:INCA-6;9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE;1,4,9,10-Tetrahydro-9,10-[1,2]benzenoanthracene-1,4-dione;9,10-[1,2]Benzeno-1,4,9,10-tetrahydroanthracene-1,4-dione;9,10-[1,2]Benzeno-9,10-dihydro-1,4-anthraquinone;9,10-[1,2]Benzeno-9,10-dihydroanthracene-1,4-dione;9,10-Dihydro-9,10-[1,2]benzeno-1,4-anthraquinone;Nsc25996
CAS:3519-82-2
Molecular Formula: C20H12O2
Molecular Weight: 284.313
InChI: InChI=1/C20H12O2/c21-15-9-10-16(22)20-18-12-6-2-1-5-11(12)17(19(15)20)13-7-3-4-8-14(13)18/h1-10,17-18H
Molecular Structure: (C20H12O2) INCA-6;9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE;1,4,9,10-Tetrahydro-9,10-[1,2]benzenoant...
Properties
Flash Point: 172.6°C
Boiling Point: 464.2°C at 760 mmHg
Density:1.38g/cm3
Refractive index:1.729
Biological Activity: Inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (K d = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT.
Flash Point: 172.6°C
Safety Data