Biological Activity: | Positive allosteric modulator selective for mGlu 2 receptors. Potentiates glutamate-stimulated [ 35 S]GTP γ S binding (EC 50 values are 1.7 and > 10 μ M for mGlu 2 and mGlu 3 receptors respectively). Devoid of any activity at mGlu 5 and mGlu 7 receptors. |