[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,(1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)- (36011-19-5)

Identification
Name:	[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,(1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)-
Synonyms:	21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E)-;Cytochalasin E; NSC 175151; [1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,[4S-(1E,4R,6S,7E,11aR,14R,14aR,15R,15aS,16aR,16bR*)]-
CAS:	36011-19-5
EINECS:	252-835-7
Molecular Formula:	C28H33 N O7
Molecular Weight:	495.56412
InChI:	InChI=1S/C28H33NO7/c1-16-9-8-12-19-23-27(4,35-23)17(2)21-20(15-18-10-6-5-7-11-18)29-24(31)28(19,21)36-25(32)34-14-13-26(3,33)22(16)30/h5-8,10-14,16-17,19-21,23,33H,9,15H2,1-4H3,(H,29,31)/b12-8+,14-13+
Molecular Structure:
Properties
Transport:	UN 1544 6.1/PG 2
Melting Point:	206 °C
Flash Point:	380.2°C
Boiling Point:	705.1°C at 760 mmHg
Density:	1.3g/cm³
Refractive index:	1.608
Water Solubility:	soluble in DMSO, ethyl acetate, ethanol, dichloromethane
Solubility:	SOL IN DICHLOROMETHANE, CHLOROFORM, ACETONE, & METHANOL; SPARINGLY SOL IN WATER
Appearance:	White powder.
Specification:	Cytochalasin E (CAS No.:36011-19-5), a member of the Cytochalasin group, is an inhibitor of actin polymerization in blood platelets. It inhibits angiogenesis and tumor growth. Unlike cytochalasin A and cytochalasin B, it does not inhibit glucose transport.Because of its antiangiogenic effect, Cytochalasin E is mentioned as a potential drug for age-related macular degeneration, a kind of blindness caused by an abnormal proliferation of blood vessels in the eye.
Packinggroup:	I
Flash Point:	380.2°C
Storage Temperature:	−20°C
Color:	CRYSTALS FROM ACETONE-HEXANE
Safety Data

[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione,3,13,14,14a,15,15a,16a,16b-octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-,(1E,4S,6R,7E,11aS,14S,14aS,15S,15aR,16aS,16bS)- (36011-19-5)

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