| Identification | |
| Name: | Pregnan-20-one,3-hydroxy-3-methyl-, (3a,5a)- |
| Synonyms: | 3a-Hydroxy-3b-methyl-5a-pregnan-20-one; 5a-Pregnan-20-one, 3a-hydroxy-3-methyl-; CCD 1042;Ganaxolone |
| CAS: | 38398-32-2 |
| Molecular Formula: | C22H36 O2 |
| Molecular Weight: | 0 |
| InChI: | InChI=1/C22H36O2/c1-14(23)17-7-8-18-16-6-5-15-13-20(2,24)11-12-21(15,3)19(16)9-10-22(17,18)4/h15-19,24H,5-13H2,1-4H3/t15-,16-,17+,18-,19-,20+,21-,22+/m0/s1 |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 185.4°C |
| Boiling Point: | 434.8°Cat760mmHg |
| Density: | 1.036g/cm3 |
| Refractive index: | 1.517 |
| Biological Activity: | Potent positive allosteric modulator of GABA A receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABA A receptors (EC 50 values are 94, 122 and 213 nM for α 2 β 1 γ 2 L , α 3 β 1 γ 2 L and α 1 β 1 γ 2 L receptors respectively). Exerts anticonvulsive effects in a broad range of animal seizure models. |
| Flash Point: | 185.4°C |
| Storage Temperature: | 2-8°C |
| Color: | white |
| Safety Data | |
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