1H-Cyclopentapyrimidine-1-propanoicacid, a-amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-,(aS)- (389888-02-2)

Identification
Name:	1H-Cyclopentapyrimidine-1-propanoicacid, a-amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-,(aS)-
Synonyms:	(S)-CPW399
CAS:	389888-02-2
Molecular Formula:	C10H13 N3 O4
Molecular Weight:	239.23
Molecular Structure:
Properties
Biological Activity:	Novel subtype-selective and weakly desensitizing AMPA receptor partial agonist (K i values are 44, 109, 223, 1890 and 2090 nM at GluR5, GluR1, GluR2, GluR3 and GluR4 receptors respectively). Exhibits potent agonist activity at GluR1 and GluR2 subunit-containing AMPA receptors (EC 50 values are 24.9 and 13.9 μM respectively) and is excitotoxic in vitro .
Safety Data

Other Product

2,3,4,5,6,7-Hexahydro-2,4-dioxo-3-phenyl-1H-cyclopentapyrimidine-1-acetamide
2,3,4,5,6,7-hexahydro-4-oxo-2-thioxo-1H-CyclopentapyriMidine-1-acetic acid
1H-Indole-5-propanoicacid,1-[2-[[(4-fluorophenyl)sulfonyl]amino]ethyl]-2-methyl-3-(3-pyridinylmethyl)-
2,3,4,5,6,7-Hexahydro-2,4-dioxo-3-phenyl-1H-cyclopentapyrimidine-1-acetic acid
2,3,4,5,6,7-Hexahydro-2,4-dioxo-N,N,3-trimethyl-1H-cyclopentapyrimidine-1-acetamide
N,N-Dimethyl-2,3,4,5,6,7-hexahydro-2,4-dioxo-3-phenyl-1H-cyclopentapyrimidine-1-acetamide
Propanoicacid, 2-methyl-,1,2-bis(acetyloxy)-5-cyano-2,3,4,5,6,11-hexahydro-3,7-dihydroxy-3-methyl-6,11-dioxo-1H-benzo[b]carbazol-4-ylester, [1S-(1a,2b,3a,4a)]- (9CI)
Spiro[cyclopentane-1,1'-[1H]indene]-4'-propanoicacid,2-[(1R,4E)-5-carboxy-1-methyl-3-oxo-4-hexenyl]-2',3',3'a,4',5',6'-hexahydro-2,4'-dimethyl-5-methylene-5'-(1-methylethenyl)-,(1R,2S,3'aR,4'R,5'S)- (9CI)
2H-1-Benzopyran-4-propanoicacid, a-amino-7-methoxy-2-oxo-
Hexanoic acid,6-[[6-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]amino]-1-oxohexyl]amino]-,2,5-dioxo-3-sulfo-1-pyrrolidinyl ester
1H-Indole-5-propanoicacid,1-[2-[[(4-fluorophenyl)sulfonyl]amino]ethyl]-3-(1H-imidazol-1-ylmethyl)-2-methyl-
1H-Cyclopentapyrimidine-1-acetic acid, 2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-
1H-Indene-4-propanoicacid, 2,3,5,6,7,7a-hexahydro-7a-methyl-1,5-dioxo-
Hexanoic acid,6-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]amino]-,2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, sodium salt (1:1)
1H-Pyrrole-2-propanoicacid, 1-(2-methoxyphenyl)-5-(4-methoxyphenyl)-
1H-Pyrrole-2-propanoicacid, 5-(4-methoxyphenyl)-
1H-Pyrrole-2-propanoicacid, 5-(4-methylphenyl)-
1H-Pyrrole-2-propanoicacid, 5-(4-fluorophenyl)-
1H-Pyrrole-3-propanoicacid, 5-(aminomethyl)-2-bromo-4-(carboxymethyl)-
Hexanoic acid,6-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]amino]-,2,5-dioxo-3-sulfo-1-pyrrolidinyl ester