| Identification |
| Name: | 4-HYDROXY-3,3-DIMETHYL-2H-BENZO[G]INDOLE-2,5(3H)-DIONE |
| Synonyms: | 4-HYDROXY-3,3-DIMETHYL-2H-BENZ[G]INDOLE-2,5(3H)-DIONE;4-HYDROXY-3,3-DIMETHYL-2H-BENZO[G]INDOLE-2,5(3H)-DIONE;BVT 948 |
| CAS: | 39674-97-0 |
| Molecular Formula: | C14H11NO3 |
| Molecular Weight: | 241.24 |
| InChI: | InChI=1/C14H11NO3/c1-14(2)9-10(15-13(14)18)7-5-3-4-6-8(7)11(16)12(9)17/h3-6,17H,1-2H3 |
| Molecular Structure: |
![(C14H11NO3) 4-HYDROXY-3,3-DIMETHYL-2H-BENZ[G]INDOLE-2,5(3H)-DIONE;4-HYDROXY-3,3-DIMETHYL-2H-BENZO[G]INDOLE-2,5(3...](https://img.guidechem.com/structure/39674-97-0.gif) |
| Properties |
| Flash Point: | 196.2°C |
| Boiling Point: | 400.8°C at 760 mmHg |
| Density: | 1.39g/cm3 |
| Refractive index: | 1.679 |
| Biological Activity: | Non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC 50 = 0.09-1.7 μ M); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo . Also inhibits several cytochrome P450 isoforms (IC 50 < 10 μ M). |
| Flash Point: | 196.2°C |
| Color: | red |
| Safety Data |
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