| Identification |
| Name: | 2-Propenamide,3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-,(2E)- |
| Synonyms: | Salubrinal |
| CAS: | 405060-95-9 |
| Molecular Formula: | C21H17 Cl3 N4 O S |
| Molecular Weight: | 479.81 |
| InChI: | InChI=1/C21H17Cl3N4OS/c22-21(23,24)19(27-17(29)12-11-14-6-2-1-3-7-14)28-20(30)26-16-10-4-8-15-9-5-13-25-18(15)16/h1-13,19H,(H,27,29)(H2,26,28,30)/b12-11+ |
| Molecular Structure: |
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| Properties |
| Density: | 1.474g/cm3 |
| Refractive index: | 1.731 |
| Biological Activity: | Cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2 α ). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC 50 ~ 15 μ M). |
| Safety Data |
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