Identification |
Name: | 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE |
Synonyms: | 4-(2'-FLUOROBIPHENYL-4-YL)-N-(4-HYDROXYPHENYL)-BUTYRAMIDE;2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE;CMPD-1 |
CAS: | 41179-33-3 |
Molecular Formula: | C22H20FNO2 |
Molecular Weight: | 349.3981032 |
InChI: | InChI=1/C22H20FNO2/c23-21-6-2-1-5-20(21)17-10-8-16(9-11-17)4-3-7-22(26)24-18-12-14-19(25)15-13-18/h1-2,5-6,8-15,25H,3-4,7H2,(H,24,26) |
Molecular Structure: |
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Properties |
Flash Point: | 307.6°C |
Boiling Point: | 585°C at 760 mmHg |
Density: | 1.229g/cm3 |
Refractive index: | 1.627 |
Biological Activity: | Non-ATP-competitive, selective inhibitor of p38 α -mediated MK2a (mitogen-activated protein kinase-activated protein kinase 2a) phosphorylation (apparent K i = 330 nM). Does not inhibit p38 α -mediated phosphorylation of the two other known p38 substrates, MBP and ATF-2. |
Flash Point: | 307.6°C |
Storage Temperature: | Store at RT |
Safety Data |
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