| Identification | |
| Name: | DPO-1 |
| Synonyms: | DPO-1 |
| CAS: | 43077-30-1 |
| Molecular Formula: | C22H29OP |
| Molecular Weight: | 340.444 |
| InChI: | InChI=1/C22H29OP/c1-17(2)21-15-14-18(3)16-22(21)24(23,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,17-18,21-22H,14-16H2,1-3H3/t18-,21+,22+/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 216.86°C |
| Boiling Point: | 434.966°C at 760 mmHg |
| Density: | 1.054g/cm3 |
| Refractive index: | 1.547 |
| Biological Activity: | Blocker of I Kur ultrarapid delayed rectifier potassium current and K V 1.5 channels (IC 50 = 0.31 μ M for rK V 1.5). Displays selectivity for inhibition of I Kur over I to (8-fold), I K1 , I Kr and I Ks (20-fold) in native myocytes and selectivity for rat recombinant K V 1.5 over K V 3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia. |
| Flash Point: | 216.86°C |
| Safety Data | |
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