| Identification | |
| Name: | Dacarbazine |
| Synonyms: | Dimethyltriazenoimidazolecarboxamide;Di-me-triazenoimidazolecarboxamide;Biocarbazine R;Dtic-Dome (TN);DTIE;Dacarbazine (JAN/USP);Imidazole-4-carboxamide, 5- (3, 3-dimethyl-1-triazeno)-;4-(5)-(3, 3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide;Carboxamide, 5-(3,3-dimethyl-1-triazeno)imidazole-4-;5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide;1H-Imidazole-4-carboxamide, 5- (3,3-dimethyl-1-triazenyl)-;4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide;5-(Dimethyltriazeno)imidazole-4-carboximide;4-(Dimethyltriazeno)imidazole-5-carboxamide;Carboxamide, 5-(3, 3-dimethyl-1-triazeno)imidazole-4-;Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-;(5Z)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide;ICDT;DIC;4-(or 5)-(3, 3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide;Deticene;1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-;4-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide;4-(3, 3-Dimethyl-1-triazeno)imidazole-5-carboxamide;5-(Dimethyltriazeno)imidazole-4-carboxamide;1H-Imidazole-4-carboxamide,5-(3,3- dimethyl-1-triazenyl)-;DTIC;Imidazole-4(or 5)-carboxamide, 5(or 4)-(3, 3-dimethyl-1-triazeno)-;Darcarbazinum; |
| CAS: | 4342-03-4 |
| EINECS: | 224-396-1 |
| Molecular Formula: | C6H10N6O |
| Molecular Weight: | 182.18 |
| InChI: | InChI=1/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+ |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | 229.7 oC |
| Boiling Point: | 456.3 oC at 760 mmHg |
| Density: | 1.48 g/cm3 |
| Stability: | Stable at room temperature in closed containers under normal storage and handling conditions. |
| Refractive index: | 1.678 |
| Water Solubility: | slightly soluble in ethanol and water |
| Solubility: | slightly soluble in ethanol and water |
| Appearance: | Yellowish or reddish powder |
| Specification: |
? Dacarbazine (CAS NO.4342-03-4), its Synonyms are (Dimethyltriazeno)imidazolecarboxamide ; 1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)- ; 4(5)-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide ; 4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide ; 4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide ; 4-(Dimethyltriazeno)imidazole-5-carboxamide ; 4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide ; 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide ; 5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide ; 5-(Dimethyltriazeno)imidazole-4-carboxamide ; AI3-52825 ; Biocarbazine ; Biocarbazine R ; CCRIS 190 ; Carboxamide, 5-(3,3-dimethyl-1-triazeno)imidazole-4- ; DIC ; DTIC ; DTIC-Dome . It is white to ivory microcrystals or off-white crystalline solid. |
| Report: |
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 184.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 (1981),p. 203.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 (1981),p. 203.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Studies (ipr); Clear Evidence: mouse, rat RRCRBU ?? Recent Results in Cancer Research. 52 (1975),1. . EPA Genetic Toxicology Program. |
| Flash Point: | 229.7 oC |
| Color: | IVORY MICROCRYSTALINE SUBSTANCE |
| Usage: | Cytostatic drug. |
| Safety Data | |
| Hazard Symbols |
T:Toxic
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