| Identification | |
| Name: | 5,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-,(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)- |
| Synonyms: | 8a(1H)-Quinazolineorthoglycolicacid, octahydro-4,5,6,7,8-pentahydroxy-6-(hydroxymethyl)-2-imino-, cyclic8a,5:8a,7-ester (7CI); Tetrodotoxin (8CI); (-)-Tetrodotoxin;5,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,octahydro-12-(hydroxymethyl)-2-imino-, [4R-(4a,4aa,5a,7a,9a,10a,10ab,11S*,12S*)]-; Araregai toxin; BJT 1; Babyloniajaponica toxin 1; Maculotoxin; PFT-1 Toxin; Spheroidine; TTX; Tarichatoxin;Tetrodotoxine; [4R-(4a,4aa,5a,7a,9a,10a,10ab,11S*,12S*)]-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol |
| CAS: | 4368-28-9 |
| EINECS: | 224-458-8 |
| Molecular Formula: | C11H17 N3 O8 |
| Molecular Weight: | 319.26798 |
| InChI: | InChI=1S/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2-,3?,4+,5+,6-,7+,9+,10-,11-/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 3462 6 |
| Melting Point: | 225 deg C dec |
| Density: | 2.78 g/cm3 |
| Refractive index: | 2.087 |
| Water Solubility: | slightly soluble in Water |
| Solubility: | slightly soluble in Water |
| Appearance: | white to beige solid. |
| Specification: | white powder Safety Statements:22-36/37/39-45-36/37 22:Do not breathe dust 36/37/39:Wear suitable protective clothing, gloves and eye/face protection 45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 36/37:Wear suitable protective clothing and gloves |
| Packinggroup: | I |
| Biological Activity: | Selective inhibitor of Na + channel conductance. Binding is reversible and of high affinity (K d = 1-10 nM). Blocks in a use-dependent manner. |
| Storage Temperature: | 2-8°C |
| Color: | white |
| Safety Data | |
| Hazard Symbols |
T+: Very toxic
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