Diglycolic anhydride (4480-83-5)

The Diglycolic anhydride with the CAS number 4480-83-5 is also called Acetic acid, 2,2'-oxybis-, cyclic anhydride. Both the systematic name and IUPAC name are 1,4-dioxane-2,6-dione. Its EINECS registry number is 224-761-5. The molecular formula is C₄H₄O₄. This chemical belongs to the following product categories: (1)Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; (2)Dioxanes; (3)Dioxanes & Dioxolanes.

The properties of the chemical are: (1)ACD/LogP: -2.06; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.06; (4)ACD/LogD (pH 7.4): -2.06; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1.81; (8)ACD/KOC (pH 7.4): 1.81; (9)#H bond acceptors: 4; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 52.6 Å²; (13)Index of Refraction: 1.45; (14)Molar Refractivity: 21.91 cm³; (15)Molar Volume: 81.5 cm³; (16)Polarizability: 8.68×10^-24cm³; (17)Surface Tension: 45.3 dyne/cm; (18)Enthalpy of Vaporization: 47.88 kJ/mol; (19)Vapour Pressure: 0.0351 mmHg at 25°C.

Uses: This chemical can react with diethylamine to prepare N,N-Diethyldiglycollamsaeure. This reaction needs solvent CH₂Cl₂ at heating condition. The reaction time is 2.0 hours. The yield is 81%.

While using this chemical, you should be very cautious. This chemical is not only irritating to skin, but also irritating to eyes and respiratory system. Therefore, you should take the following instructions. Firstly, you should wear suitable protective clothing. Then you should avoid this chemical contact with skin and eyes. Finally in case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C1OC(=O)COC1
(2)InChI: InChI=1/C4H4O4/c5-3-1-7-2-4(6)8-3/h1-2H2
(3)InChIKey: PIYNUZCGMLCXKJ-UHFFFAOYAT